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Current evidence is mixed and limited

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Similarly, beta-lactams and fluoroquinolones, the first-line antibiotics, have been found to play a significant role in the AMR burden globally 33,34

The Hp1/2 proteins form different oligomers, such that a dimeric Hp11 molecule can bind two haemoglobin dimers, while the polymeric Hp21 and Hp 22 molecules have the capacity to bind greater numbers of haemoglobin dimers (Morton et al., 2006)