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These cationic arginine-rich peptides (CARP) decrease glutamate-induced excitotoxicity and neuronal Ca 2+ influx by decreasing surface expression of GluN2B, activate pro-survival pathways, and preserve neuronal mitochondrial integrity with minimum in vivo toxicity 94,95

MiR-17-5p, a miRNA highly expressed in hepatocellular carcinoma, activates the Wnt/-catenin pathway and exacerbates radiation-induced liver fibrosis [102]