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Description

Mitochondrial quality control in human health and disease

The peptide stimulates expression of early growth response 1 (EGR-1) gene, which regulates cytokine and growth factor generation along with early extracellular matrix formation, while simultaneously inducing its repressor NAB2 to prevent excessive angiogenic signaling

The NHS access journey, should CagriSema receive approval, would then follow a separate NICE appraisal process the same pathway that Wegovy and Mounjaro have navigated