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Chronic inflammation and the growth hormone/insulin-like growth factor-1 axis

DOI: 10.1210/endrev/bnad019 Imai S & Guarente L (2014) Trends in Cell Biology , 24(8): 464471 (npj Aging) Foundational review confirming the intimate connection between NAD+ availability and sirtuin activity as a conserved ageing/longevity regulatory axis

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Regular serum B12 monitoring is not routinely necessary once stable on replacement therapy, as levels become artificially elevated and unreliable