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doi: 10.3390/ijms22179274 41 LiangYWuJWangWXieHYaoS

Tumor necrosis factor- (TNF-), another key host inflammatory mediator, can induce HIF-1 expression in macrophages harvested from wounds and cultured under normoxic conditions (Albina et al., 2001), providing another link between inflammation and HIF stabilization in immune cells