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304 WangT.QinZ.-Y.WenL.-Z.GuoY.LiuQ.LeiZ.-J.et al (2018)

Importantly, it also led to a reduction in HIF-1 expression, indicating that restoring local oxygen availability can directly influence gene regulation (Okniska et al., 2024)

VEGF-A can also bind the pro-angiogenic VEGF-receptor 1 (VEGFR1), a kinase-impaired receptor with higher affinity for VEGF-A as compared to VEGFR2

These include the production of red blood cells and the maintenance of nerve cells

see Methods and supplementary Table 4) in our paired LNCaP-AD/AI, LAPC4-AD/AI and LAPC9-AD/AI xenograft tumors in which all 3 AI models upregulated BCL-2 (Fig