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Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders

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doi: 10.1007/bf01535722 22 HolmesELiJVAthanasiouTAshrafianHNicholsonJK

Even though it is possible that CD38 might directly affect the brain, targeting CD38 abrogated disease-associated T H 17 cell immunity, potentially by breaking meningeal to cortical communication via modulation of IL-17A/IL-1 crosstalk (Fig

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