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As it turns out, your pattern of melatonin secretion is slightly abnormal

Also, phenytoin is an inducer of CYP450 isozymes, is metabolized by CYP450 enzymes, and is highly protein bound

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Given that fMRI reactivity of the brain depends entirely on regional oxygenated hemoglobin levels, it is not completely clear whether the observed reductions in reactivity of in the brain are entirely due to underlying reductions in neural responses or at least partially due to decreased cerebrovascular responses