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Copper is essential for several enzymatic processes in the body, including those related to tissue repair and collagen synthesis

Inhibition of NADH-Linked Mitochondrial Respiration by 4-Hydroxy-2-Nonenal

The in-depth analyses of the results revealed that the proteins enolase, neuropolypeptide h3, ATP synthase, and fructose bis-aldolase (FBA) were identified as oxidized in brain from subjects at each stage of AD, late-stage AD, EAD, and MCI, consistent with the concept that their oxidation is an early event in and may contribute to progression of AD

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