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Possible reactions may include digestive discomfort, headaches, skin reactions, or rare allergic responses

The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

Tirzepatide, by contrast, activates both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptors simultaneously, producing rapid satiety signaling, improved insulin sensitivity, and accelerated weight reduction

Gently tap the side of the syringe barrel with your finger

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