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(A) Schematic illustration of the workflow used, in which 3T3-L1 adipocytes were treated with Mock or MST6-I secretome/CM to generate transdifferentiated white adipocytes (TWAT)(Mock) or TWAT(MST6-I)

The most commonly used medical skin whitening approach involves glutathione therapy

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Finally, we highlight potential treatments that target cerebral metabolism, such as nutraceuticals, ketone bodies and dietary interventions