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Description

In tumours, hypoxia is observed in cancer cells that reside more than 70150 m away from a perfused blood vessel

CH25H expression in these cells is induced by factors such as lactic acid, acidic pH, interleukin-4 (IL-4) or interleukin-13 (IL-13), which act through the signal transducer and transcription activator 6 (STAT6)