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Vitamin B12 , or cobalamin, is a type of B vitamin

Intra-assay variability was CV 7.28 %, and inter-assay variability was CV 8.2% for conditioned medium assay

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Although high selectivity of PAG for CSE over CBS has been reported (i.e., an IC 50 of 40 M for the CSE-catalyzed reaction using 1 mM of cysteine as the substrate, with no detectable inhibition of CBS even at 10 mM PAG), it also inhibits several other PLP enzymes, such as aspartate aminotransferase, alanine aminotransferase, and methionine -lyase (Sun et al., 2009)

Safety and efficacy of (+)-epicatechin in subjects with Friedreichs ataxia: A phase II, open-label, prospective study

10.1038/s41568-019-0156-2 21 FangY.GongA