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Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

However, there is evidence that free-radicals such as NO cause rapid damage to certain cell macromolecules that are involved in the ETC system, which in turn will decrease production of ATP and may be implicated in cytotoxic effects in the central nervous system (Lizasoain et al., 1996)

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Oxidative stress, characterized by an accumulation of ROS, is a pivotal factor influencing embryo development