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Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

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Overdose symptoms are severe, prolonged, and disablingintense vomiting, incapacitating abdominal pain, and symptoms that worsen rather than improve over 24-48 hours signal overdose and require medical evaluation

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Tusa N.V., Abuelo A., Levy N.A., Gandy J.C., Langlois D.K., Cridge H

Although this may reflect differences in absorption, distribution, and elimination, differences in drug metabolism also plays a role