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Furthermore, curcumins antioxidant action protects oral mucosal cells from therapy-induced oxidative stress, and its anti-microbial effect may help prevent secondary infections of ulcerated mucosa (Amatto et al., 2025)

In metabolic disease, nutrient overload and ER stress elevate H 2 O 2 /O 2 , coupling lipotoxicity to ferroptotic risk when labile iron expands (Schieber and Chandel 2014)

Emerging research suggests probiotics may support digestive health and immune function while indirectly supporting liver health, although more canine-specific studies are needed

By transferring or transplanting exogenous healthy mitochondria to replace damaged ones, cellular energy metabolism can be restored, neuronal survival improved, and neurological function recovered, offering a multidimensional therapeutic strategy for IS

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[7] Although cannabis withdrawal is rarely dangerous, it can be distressing and very uncomfortable, and it is officially recognized in the DSM-5