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This disruption of core sleep-wake regulatory circuitssuch as the hypothalamic-preoptic area and locus coeruleusultimately leads to SF (Walker and Borniger, 2019

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Originally developed for use with GAC, the RSSCT technique uses crushed GAC and shorter EBCTs to quickly predict operating capacity

*Correspondence: Liqun Jiao, [email protected] Wang, [email protected] Yang, [email protected] These authors have contributed equally to this work This article was submitted to Atherosclerosis and Vascular Medicine, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The lack of equitable access, behavioral and cultural change, regulation of quality of commercial products and methodological fortification of the evidence base are rather numerous issues that are to be solved yet they can be addressed in collaboration of the research, policy, industry and civil society