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Early research shows that taking vitamin B12, aged garlic extract, folic acid, vitamin B6, and L-arginine daily for 12 months slows the progression of clogged arteries and improves blood vessel function in people at risk for clogged arteries

doi: 10.1016/S0009-9120(01)00196-5

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Among these, the downregulation of circSnx12 induces iron overload by releasing miR-224-5p to downregulate FTH1 levels [139]

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