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The clinical probability of pulmonary embolism is low, less than 15%, for a score of less than 4.5 (6)

The Cardiac Electrical Cycle (Electrical Cascade) The cardiac action potential represents the sequence of ion exchanges that result in the successive depolarization and repolarization of the cardiac myocyte, culminating in muscle contraction (4)

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12,13 Subsequent to the discovery of metformin, other trials were published on the structurally similar biguanides, namely phenformin and buformin