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Given the peptide's short plasma half-life (~0.51 hour), daily dosing maintains more consistent exposure to the peptide's gene-expression-modulating effects

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BPC-157s effects on angiogenesis and growth factor expression raise theoretical concerns about possible effects on tumor growth or progression

Identified cellular targets through which PKA activation produces a bronchodilator effect include: MLCK: Phosphorylation of myosin light chain kinase (MLCK) by cAMP-dependent protein kinase (PKA) decreases the affinity of the kinase for Ca2+ and calmodulin , resulting in a decrease in MLCK activity

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