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During mitochondrial glutaminolysis, glutamine is transported into the mitochondrial matrix via the mitochondrial glutamine transporter SLC1A5 variant and then converted to glutamate (Glu) by glutaminase (GLS), releasing ammonium ions [80]

Standard curves for S -THIQ and R -THIQ were prepared using supernatants from assays performed as described in the IRED characterization with biosensor-linked fluorescence assays

doi:10.3892/etm.2019.8393 Capasso A

Accordingly, a marginal alteration in the intracellular concentration of GSH may not influence the catalytic activities of seleno-GPxs under in vivo conditions

Given sulforaphanes ability to activate multiple cytoprotective mechanisms, sulforaphane is emerging as a promising therapeutic for multiple neurodegenerative and neurodevelopmental disorders

Mol Neurobiol Molecular Neurobiology 2012).RemarkabIy, Dihexa completely restores performance in the rope hang test in 6-OHDA lesioned rats after two weeks treatments when delivered by the intraperitoneal route (Figure 48)