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Intake of large amounts of fat and monosaccharides may lead to intestinal biological disorders, resulting in increased intestinal barrier permeability and ultimately poor sperm quality and impaired spermatogenesis (66)

However, because the intestines contain an enzyme that degrades glutathione, this can reduce the bioavailability of glutathione in food and also most oral supplements

10.1097/IJG.0b013e31819c46b1 Sano H, Namekata K, Kimura A, et al.: Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma