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doi: 10.1016/S0305-4179(01)00055-9

Alorabi, M., Cavalu, S., Al-Kuraishy, H

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Supplementary material The Supplementary Material for this article can be found online at: FIGURE S1 Pravastatin treatment did not affect liver histology of LDLr -/- mice

Even though the BBB is a highly selective membrane intended to protect the brain from toxins and invading pathogens, despite its semipermeable nature, the BBB is mostly impenetrable to most drugs, especially large or hydrophilic molecules, which restrict their entry into the brain and bloodstream