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Risks from Concomitant Use with Opioids Advise both patients and caregivers about the risks of potentially fatal respiratory depression and sedation when alprazolam tablets are used with opioids and not to use such drugs concomitantly unless supervised by a healthcare provider

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This makes them useful as reference compounds when designing new studies or replicating earlier work

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Statistics and reproducibility Statistical significance of the experimental data was verified using one-way ANOVA and the Tukey method for comparison of means

Table 2 Dry matter (DM) of digesta in different gastrointestinal sites on d5 and d14 ( n = 68)