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doi: 10.1152/ajpendo.00579.2013

I answered the question instantly and let out a huge grin

A.BoyerL.AignerS.et al

SOD1 was the first gene linked to ALS (Rosen et al., 1993), thus there has been intensive research into pathogenic mechanisms associated with mutant SOD1 (Rosen et al., 1993)

Basically, it is very common that pathology precedes pain

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