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In contrast to our in vitro results, treatment with MitoQ, DPI, or their combination did not produce notable effects on tumor size reduction, even at the highest tolerable doses ( Figure 9A )

Phytochemicals have, thus, become a major research focus not only for weight loss but also for health-improving properties as they have been found to act through several overlapping mechanisms like AMP-activated protein kinase (AMPK) activation, lipogenic inhibition, adipogenic transcription factors suppression, fatty acid oxidation elevation, and inflammation reduction

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