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During this step, known as the propagation phase,10 TF becomes less important, because the reaction is mainly driven by the FVIIa/FXa and FVa/FXa complexes.18,24 To further understand to what extent tumor cell TF contributes to thrombin generation, two different strategies were used: (i) inhibiting cell-associated TF with a specific anti-TF antibody, and (ii) performing the assay in FVII-deficient plasma

In cancer therapy, TCM components exert antitumor effects by modulating the redox balance and immunometabolism in the tumor microenvironment (TME)

In these organisms, several abilities of omega-3-PUFA action on endometriotic foci have been presented, including the reduction of endometrial lesions, lowering of the levels of IL-6 [141], and the reduction of COX-2 and Ph-3-mitotic marker expression

Ligation between polysaccharides and PRRs activates the MAPK and NF-B signaling pathways, promoting DC maturation (66), enhancing their antigen-presenting capacity, and subsequently directing the differentiation of T cells toward Treg subsets, while facilitating B-cell secretion of secretory immunoglobulin A (67)

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S., Chignell, C