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Vitamin E deficiency may result in neuropathies, as well as progressive necrosis of the nervous system and muscles

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Representative photographs of the treated spots are shown in Fig

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In addition, both riboflavin and PLP are essential determinants of the kynurenine pathway which influence glutamate receptors, hence, glutamate excitotoxicity potential, as shown in Section Riboflavin as a Determinant of the Kynurenine Pathway. Concerning PD, glutamate excitotoxicity contributes to dopaminergic neuronal loss (84)

HeLa (ATCC, #CCL-2), HEK293T (ATCC, #CRL-11268), and A549 (ATCC, #CCL-185) cells were grown in DMEM (Invitrogen) supplemented with 10% FBS (FBS