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Regulation of phosphatidylserine exposure in red blood cells

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Results: Bid-/- Bim-/- Puma-/- Bcl-xL(-/-) Mcl-1(+/-) mice showed significantly lower levels of serum ALT and smaller number of TUNEL positive hepatocytes than Bid-/- Bim-/- Puma+/+ Bcl-xL(-/-) Mcl-1(+/-) mice

We identified the marine-derived small molecule MHO7, which acts as a potent immunogenic cell death (ICD) inducer through the endoplasmic reticulum (ER) stress-C/EBP-homologous protein (CHOP) pathway, to treat TNBC