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2 For example, the holistic blogosphere is full of articles linking small intestine bacterial overgrowth (SIBO) to B12 deficiency

Dietary modifications are essential, including encouraging patients to consume small, frequent meals to reduce gastric distension and improve emptying, adopting a low-fiber, low-fat diet to minimize delays in gastric emptying, and incorporating liquid nutrients that are easier to digest

Follow-up Repeat broad markers after 8-12 weeks if symptoms change or the protocol continues

When to seek qualified medical care Severe injection-site reaction, rash, breathing difficulty, sudden swelling, or any allergic-type response after Semax administration is a medical concern, not a protocol question

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doi:10.1186/s13023-022-02179-y