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Many of the drugs used to lower plasma LDL levels, such as the statins, ezetimibe, PCSK9 inhibitors, bile acid sequestrants and bempedoic acid lower plasma LDL levels by increasing the number of hepatic LDL receptors (57)

doi: 10.1016/j.molmet.2019.06.026 49 SabariBRZhangDAllisCDZhaoY

doi: 10.2147/JEP.S237487

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Weight loss was reportedly continuous, with an average reduction in body weight ranging from about 4 percent after one year of treatment to more than 13 percent after five years