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The newly identified features of the disease increasingly regard PAH as a multipronged disease involving multiple points of interaction between genetics, metabolomics, imbalance of vasoconstrictor and vasodilator responses, endothelial and smooth muscle dysfunction, thrombosis and platelet dysregulation, and mitochondrial and miRNA abnormalities

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In mice, repression of Fxr decreases the expression of Cyp7a1 , hepatic bile salt synthesis, and hence cholesterol solubility

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

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RNAi-mediated silencing of a novel Ascaris suum gene expression in infective larvae