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Takeaway: It is a promising area of anti-aging research, but it remains largely theoretical in living humans

The results showed that the solubility, swelling power, crystal morphology and functional properties of TBS modified by alcohol-alkali method, drying method and ball milling method were improved to some extent (63)

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Brebner K, Wong TP, Liu L, Liu Y, Campsall P, Gray S et al (2005)

When applied consistently: dark spots may fade hyperpigmented areas may lighten uneven tone may improve However, if irritation occurs: inflammation may increase rebound pigmentation may happen sensitivity may rise Topical ingredients require careful skin barrier management

da Costa Domingues CE, Ansaloni LS, Gregorc A, da Silva ECM