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Their recommendations are based on a systematic literature search that focused on the incidence and severity of neuropathy, patient-reported outcomes and the patients quality of life

E., Aguilar, C

Autoimmunity (1993) 16:2517

J Appl Physiol 2015;119(8):944-51

The priming step is triggered by the detection of pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs) via Pattern Recognition Receptors (PRRs) such as Toll-like Receptors (TLRs) or NOD-like Receptors (NLRs)

1,2 A lower dosage was less effective, but its use in combination with other medications, such as amitriptyline, or with complementary/alternative methods, such as acupuncture, has provided relief