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Few studies have shown that overexpression of IGF-1 increases cancer risk through activation of the IRS/Akt/MAPK pathway [31, 80, 81, 120, 185]

However, an increasing number of studies have shown that monocytes/macrophages may also develop memory capabilities similar to those of the adaptive immune system after exposure to pathogens (305)

As per FDA Philippines definition, a Food/Dietary Supplements refers to processed food product intended to supplement the diet that bears or contains one or more of the following dietary ingredients: vitamin, mineral, amino acid, herb, or other dietary substance of botanical, animal, artificial or natural origin to increase the total daily intake in amounts conforming to the latest Philippine recommended energy and nutrient intakes or internationally agreed minimum daily requirements

Polyphenols are widely present in nature and can be classified into volatile phenols and non-volatile phenols based on their volatility

ELISA for LCN2 Serum LCN2 levels were measured using the DuoSet ELISA for Mouse Lipocalin 2 (DY1857-05, R&D Systems, Bio-Techne), according to the manufacturers protocol