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The dimers of NF-B are sequestered in the cytosol through noncovalent interactions with inhibitory proteins termed IBs [54, 55, 103, 104]

& Rajangam, J

This condition is often linked to lifestyle factors such as poor diet, obesity, and excessive alcohol consumption

The primary regulating mechanisms during ferroptosis are then briefly discussed, and we conclude by summarizing the development of a number of novel therapeutic strategies used to treat HCC in recent years