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According to the American Cancer Society (ACS), it can have a Chemotherapy injections may cause typical injection site reaction symptoms, including: skin discoloration swelling itching tenderness warmth However, chemotherapy drugs sometimes cause a symptom known as extravasation, which is when the medication leaks from the vein and into the surrounding tissue

A good provider should help you choose whats appropriate, rather than pushing injections for everyone

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The Z-track method is recommended to administer IM injections as a way to reduce local tissue irritation (Astle & Duggleby, 2019)

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