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Micro-CT data were acquired using Bruker Skyscan 1276 (Bruker, Billerica, MA, USA) with the parameters as follow: 100 KV, 80 A, and 18.4 m/slice

The activation of hypothalamic-pituitary-testicular axis in puberty induces expression of androgen receptor (AR) and stimulates secretion of testosterone and DHT 9,43,44 , which finally lead the penile growth spurt 9,43,45