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Furthermore, mutations in the juxtamembrane domain led to tumorigenesis in an in vitro trial (Graveel et al., 2013)

J Toxicol Clin Toxicol

121 Ferroptosis In recent years, a series of studies have shown that p53-associated metabolic activity is also important for its antitumor activity

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According to studies, NAC may help lower elevated levels of homocysteine in the body, helping convert this amino acid into its active proceeding form

So far, iron chelators and lipophilic antioxidants have been the principal approaches of suppressing ferroptosis [105]