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Under physiological conditions, intracellular reactive oxygen species (ROS) act as signaling molecules involved in processes such as proliferation and differentiation, with their production and clearance maintaining a dynamic balance

For instance, HHcy promotes the intracellular accumulation of SAH and reduces the SAM/SAH ratio, ultimately leading to global DNA hypomethylation [53]

doi:10.1038/452707a

Science 255 , 306312 (1992)

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