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S2N-In an optional embodiment, the base used in S2 includes any one of sodium bicarbonate, potassium bicarbonate, sodium carbonate, potassium carbonate, sodium hydroxide, N-methylmorpholine, pyridine and triethylamine, more It is preferably any one of sodium carbonate, potassium carbonate and sodium hydroxide, more preferably sodium hydroxide

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doi: 10.3389/fnut.2025.1587246 Received 07 March 2025 Revised 16 November 2025 Accepted 28 November 2025 Published 17 December 2025 Volume 12 - 2025 Edited by Ingrid Lofgren, University of Rhode Island, United States Reviewed by Sergio A

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doi:10.1016/j.jss.2004.07.251 20

CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells