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A cross-sectional study found that in patients receiving secondary cardiovascular prophylaxis, the consumption of legumes had a negative correlation with blood pressure, mediated by characteristics like insulin resistance and obesity (de Almeida et al., 2022)

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Subsequently, methyl-binding proteins (such as MeCP1, MeCP2) recognize and bind to methylation sites, recruit chromatin remodeling factors to interpret methylation patterns, and regulate gene accessibility [14]