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Moreover, these multi-protein complexes are continuously exposed to a GSH-depleted environment in Gclc -deficient FoB, which might alter protein folding or their targeting to the mitochondria

Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf 2

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The clinical significance of these findings is not known

During translation, each protein is synthesized as a linear chain of amino acids or a random coil which does not have a stable 3D structure

The coordination polymers, composed of ferric ions and curcumin at an ultrasmall nanoscale, exhibit blood-brain barrier permeability, which can effectively scavenge free radicals, inhibit neuroinflammation and restore mitochondrial function