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Every breakthrough begins with a question, followed by years of research, testing, collaboration, and refinement

Waltham: Elsevier Academic Press

It is the physicians responsibility to encourage families to seek safe, effective, evidence-based interventions

Beyond simple biomechanics, where each 1 kg of weight gain multiplies knee joint load by 34 kg, accelerating cartilage wear and activating pathogenic pathways like Wnt/ -catenin, the endocrine function of fat is paramount (14, 15)

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