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However, this test is not widely available

Pharmacogenomics 5 : 11511162 Worzalla JF, Shih C, Schultz RM (1998) Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514

Nevertheless, we cannot exclude that the observed effect was driven by the nonsignificant group difference in CPZ equivalents

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Among the reviewed studies, only two reports investigated intra-brain distribution of the released parent drug after prodrug dosing