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Consider the following loop: Mitochondrial dysfunction impairs ATP production and redox regulation This triggers neuroinflammation and epigenetic dysregulation Which in turn amplifies oxidative stress , weakening mitochondrial resilience further Leading to systemic symptoms: seizures, sleep disturbance, GI dysmotility, developmental regression Importantly, this loop is not a death spiralit is a therapeutic entry point

Finally, future perspectives are proposed to guide the rational design and practical implementation of MOF-enabled agrochemical technologies, emphasizing green synthesis, cost reduction, scalability, and farmer adoption

doi: 10.1016/j.coph.2022.102268

Lu CL, Liao MT, Hou YC, Fang YW, Zheng CM, Liu WC, et al

To study the responses of the glutathione-related genes to the heavy metal stress at different time points, above A

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