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With odd-chain fatty acids, additional enzymes are required for complete oxidation, and propionyl-CoA from the last cycle can be metabolized to succinyl-CoA, which can then enter the citric acid cycle

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Advanced lipid peroxidation end products in oxidative damage to proteins

4il, Extended Data Fig

Patients who remain at lower doses (2.55 mg) due to side effect concerns may not achieve optimal therapeutic benefit

Beyond treating some of its symptoms, there has never been a curative Peyronies treatment