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In aged mouse models, researchers observed that FOXO4-DRI administration was associated with changes in senescence biomarker levels and functional parameters

Dermatomes should not be confused with the cutaneous nerves in the limbs, which may contain fibers from more than one spinal nerve and may involve more than one dermatome because of the redistribution of spinal nerves that occur in the brachial and lumbosacral plexuses

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It's a mechanical and neurological intervention

Moreover, the senescence phenotype depends on specific pathologies or tissues, making the identification of selective markers essential for the development of new senolytic drug families

Problemy tuberkuleza i boleznei legkikh, (9), 3033