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This process helps **delay muscle fatigue, improve endurance**, and is **vital for normal heart function**

Many people who are overweight, insulin resistant, diabetic, or have a condition that stems from chronic inflammation, also accumulate fatty deposits in and around the liver, which is why NAFLD has skyrocketed in recent decades

Both dioxododecenoic acid and dioxooctenoic acid also form TOG-like GSH adducts Citation[102]

Chen ZS, Tiwari AK

In addition, loss of female sex hormones during menopause constitutes an additional susceptibility factor that can potentially heighten the negative impact of APOE 4 on female brains (Zhao et al., 2016