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Imagine trying to carry a delicate piece of paper through a rainstorm

Zhonghua Yi Xue Za Zhi, 78,2,pp.101-104

Microbiome 5 , 14 (2017)

A multiplicity of different oxysterols is synthesised in cells by sequential reactions with oxygenases, but because of the presence of the double bond in the 5,6position, oxysterols can be formed rapidly by non-enzymatic oxidation (autoxidation) of cholesterol and cholesterol esters within tissues to many different oxygenated derivatives